2009-02-10
Based on commercially available amphiphilic compounds, we have synthesized some bisphosphonates combining different PEG and perfluoroalkyl chains (07-301 and 07-302) to confer mixed properties to coated surfaces.
Surfactis is dedicated to the development and the marketing of nanocoatings for metallic and mineral surfaces functionalization.
Based upon our proprietary technology and know how in the field of nanotechnology, we have developed functional nanocoatings with unique properties and product characteristics (3 patents pending).
As of today, the company is specialized in surface functionalization in the following fields:
Hydrophobic Bisphosphonate
"Self-Assembled Monolayers of Bisphosphonates: Influence of Side Chain Steric Hindrance"
Langmuir - Published Online: 25 Jun 2009
Hydrophobic and oleophobic bisphosphonates ultrathin layers (less than 5 nm) can be deposited on material such as Titanium ,Stainless Steel and Silicon in a highly controled manner only by contacting the substrate with aqueous or organic solutions of bisphosphonates.
Cell Adhesion
"In vitro kinetic study of growth and mineralization of osteoblast-like cells (Saos-2) on titanium surface coated with a RGD functionalized bisphosphonate"
Journal of Biomedical Materials Research - Published Online: 7 Apr 2009
RGD grafted bisphosphonates have been successfully used for cell recognition, adhesion and differentiation in an osteoconduction and osseointegration application.